Vol. 7, Issue 2, Part A (2025)

Ethanolic extracts from the aerial parts of Amorphophallus paeoniifolius were investigated for their anthelmintic activity against Pheretima posthuma. The extract was tested at concentrations of 25, 50, and 100 mg/mL by evaluating the time taken to induce paralysis and death in the worms. The extract exhibited marked anthelmintic effects, with the most potent activity observed at 100 mg/mL. Piperazine citrate at 25 mg/mL was used as the standard reference, while distilled water served as the control. The extract demonstrated both vermifuge (paralyzing) and vermicidal (killing) effects on the earthworms. Furthermore, the extract was formulated into an oral suspension at an effective concentration of 100 mg/mL, and its anthelmintic efficacy was compared with that of a commercially available Piperazine citrate formulation.