Red Paper
Contact: +91-9711224068
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
International Journal of Pharmacognosy and Pharmaceutical Sciences
Peer Reviewed Journal

Vol. 7, Issue 2, Part A (2025)

Preparation of alcoholic and aqueous extract of Caper leaves as an antibiotic against coliform bacteria

Author(s):

Maha Abdulla Kamel, Mohammed Sattar Nawrooz, Jamal Salman Chiad, Firas Aziz Rahi, Hatam Hussein Rumaidh, Hashim Mohamed Zahrao, Mohammad Kalaf Saber and Abeer Nazar Jumaa

Abstract:

The active compounds of the alcoholic and aqueous leaf extracts of the Caper plant (Capparis spinosa) were selected, and the results showed the presence of seven types of active compounds, namely (tannins, carbohydrates, phenols, flavonoids, soaps, alkaloids, coumarins). The pH of the alcoholic, aqueous extracts was found (5.5, 5.97, respectively. Different concentrations were prepared and measured at (270 nm) wavelength for both alcoholic and aqueous extracts, and the standard curve was drawn for them according to the values ​​of absorbance versus concentration using a spectrophotometer. The results of analyzing the alcoholic and aqueous extract of Caper using GC (Gas chromatography) showed the presence of four main peaks for the alcoholic and aqueous extracts. In these compounds, some groups have biological activity such as tocopherol, antioxidants, and palmitic acid. The inhibitory effect of the aqueous and alcoholic extract of Caper against Escherichia coli was conducted in comparison with the antibiotic Gentamicin at different concentrations ranging from 1.25 to 20 mg/ml, and the highest inhibitory effect was at a concentration of 20 mg/ml where it matches the effect of Gentamicin with an inhibition diameter of 27 mm.

Pages: 21-26  |  497 Views  81 Downloads


International Journal of Pharmacognosy and Pharmaceutical Sciences
How to cite this article:
Maha Abdulla Kamel, Mohammed Sattar Nawrooz, Jamal Salman Chiad, Firas Aziz Rahi, Hatam Hussein Rumaidh, Hashim Mohamed Zahrao, Mohammad Kalaf Saber and Abeer Nazar Jumaa. Preparation of alcoholic and aqueous extract of Caper leaves as an antibiotic against coliform bacteria. Int. J. Pharmacognosy Pharm. Sci. 2025;7(2):21-26. DOI: 10.33545/27067009.2025.v7.i2a.171