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International Journal of Pharmacognosy and Pharmaceutical Sciences

Vol. 6, Issue 1, Part B (2024)

Formulation and evaluation of polyherbal oleogel for hair with its antimicrobial and total phenolic content

Author(s):

Ganesh Dadaso Bagal, Priya Khape, Suraj Santosh Bagul, Priya Dada Bagul, Aqsa Ashfaq Badhane and Sayalee Uday Baikar

Abstract:

This study aims to formulate and evaluate polyherbal oleogels for hair incorporating Trigonella foenum-graecum, Ficus bhengalensis, and Murraya koenigii. The oils used were prepared using the traditional Ayurvedic taila pak method. The key focus was on assessing the antimicrobial properties and total phenolic content of these oleogels. The taila pak method, involving slow heating and meticulous preparation, was utilized to extract oils from Trigonella foenumgraecum, Ficus bhengalensis, and Murraya koenigii. These oils were subsequently used to formulate oleogels using an aerosol based technique, ensuring a uniform and stable gel matrix. The polyherbal oleogels were then characterized for their physicochemical properties, including viscosity, texture, and stability. The antimicrobial properties of the formulated oleogels were tested against bacterial strains using agar diffusion. The results demonstrated significant antimicrobial activity, particularly against pathogenic bacteria like Staphylococcus aureus and Escherichia coli, which are present in hair shafts. The total phenolic content of the oleogels was measured using the Folin-Ciocalteu reagent method. The oleogels showed a high phenolic content, which correlates with their potent antimicrobial activities. Spectrophotometric analysis confirmed the presence of phenolic compounds, including flavonoids and tannins. The polyherbal oleogels exhibited excellent antimicrobial properties and a high total phenolic content. The taila pak method was effective in enhancing the extraction of bioactive compounds from the herbs, contributing to the oleogels' efficacy. The aerosol formulation technique ensured a consistent distribution of active ingredients within the gel, maintaining stability and bioavailability. The study successfully formulated polyherbal oleogels with significant antimicrobial and antioxidant properties, attributed to their high phenolic content. Combining traditional Ayurvedic oil extraction with modern aerosol formulation techniques offers a promising approach for developing effective herbal therapeutics. Further research is recommended to explore the clinical applications and long-term stability of these oleogels.

Pages: 76-83  |  131 Views  60 Downloads


International Journal of Pharmacognosy and Pharmaceutical Sciences
How to cite this article:
Ganesh Dadaso Bagal, Priya Khape, Suraj Santosh Bagul, Priya Dada Bagul, Aqsa Ashfaq Badhane and Sayalee Uday Baikar. Formulation and evaluation of polyherbal oleogel for hair with its antimicrobial and total phenolic content. Int. J. Pharmacognosy Pharm. Sci. 2024;6(1):76-83. DOI: 10.33545/27067009.2024.v6.i1a.149