Vol. 6, Issue 1, Part A (2024)

Guava (Psidium guajava) is an evergreen bush or little tree of the family Myrtaceae, commonly grown in common tropical and subtropical regions. Tannins, flavonoids: quercetin, a pentacyclic triterpenoid, saponins, carotenoids, lectins, leucocyanidin, ellagic acid, oleanolic acid, triterpenes, and ursolic acid are some of its essential phytoconstituents. 
Various parts of the plant are reported to have pharmacological properties and are used to cure ailments like malaria, gastroenteritis, spewing, and looseness of the bowels, diarrhea, wounds, ulcers, toothache, sore throat, and swollen gums. The plant has also found use in treating illnesses such as diabetes, hypertension, and obesity. The present study aims at formulation of the extract-loaded microparticles from Psidium guajava leaf extract and cellulose polymers, and their evaluation. The continuous hot extraction was done using a soxhlet extractor. The encapsulation was by using cellulose, coconut oil, and castor oil. The micromeritic studies showed good flow properties of the microparticles. The SEM, DSC, and XRD analyses depicted that the surface of microparticles was smooth, showing endothermic peaks revealing that the microparticles are amorphous in nature.