Umar Meleh Umar, Lukman Muhammad Yunusa, Ibrahim T Babalola
In this study, three different solvents of different polarities were used to extract flavonoids and tannins from parkia biglobosa stem bark which were further subjected to antibacterial activity using four strains of bacteria. The antibacterial studies showed inhibition zones exhibited by the extract against the tested bacteria ranged between 27.5-57.5 mm (E. coli), 30-62.5 mm (B. subtilis) 22.5-50mm (S. aureus) and 25-60mm (S. typhi.) as compared to 21-45mm for the control Ciprofloxacin. Flavonoid fractions of all the three different polarity extracts showed higher zones of inhibition; in some cases, higher values than the control while others are competing with it. These results were taken to indicate that crude flavonoid fractions at 200mg/ml had the highest antibacterial activity and therefore the extracts can be used as antimicrobial agents. Also, these antibacterial activities may serve to explain and support the continued use of the P. biglobosa stem bark for treating cuts, wounds and other disease conditions by traditional medicine men.
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