International Journal of Pharmacognosy and Pharmaceutical Sciences

Vol. 1, Issue 1, Part A (2019)

Pharmacological activities of hybrid derivatives of -s-triazine: A review

Author(s):

Vivek Shukla, Manish Pathak, Ganesh P Mishra and Rupesh Kumar Pandey

Abstract:

Heterocyclic compouds portray as a major part in medicinal chemistry. Distinct derivatives of heterocyclic compounds are effectives for the numerous medicinal activity. S-triazine is the earliest known heterocyclic compouns. They are available in cheap price and have distinct biological activity. Because of this researchers get attracted toward this heterocyclic compound for the synthesis of newly derivatives. They are weak base and utilize to make a potent drug, & have a different pharmacological actions. Triazine compounds are six membered hetrocyclic compound bearing triple nitrogen atoms. Based on the position of a nitrogen atoms there are 3 different triazines compound called as 1, 2, 3 triazine, 1, 2, 4 triazine, & s- triazine respectively. TriazineS are the significant core structure with bioactive characteristics. Number of triazines derivative are synthesize and assess for it abundant biological activities. Several derivative of triazine are better and have higher pharmacological action when compared to the standard drugs. The triazine reveals broad biological actions comprising antimicrobial, PI3K inhibitors, Antileshmanial, Anticancer, Anti HIV, Anti Plasmodial, Anti TB. Thus the triazines are believed to be the lead molecule for drug design and for drug discovery.

Pages: 42-49  |  31 Views  12 Downloads

How to cite this article:
Vivek Shukla, Manish Pathak, Ganesh P Mishra and Rupesh Kumar Pandey. Pharmacological activities of hybrid derivatives of -s-triazine: A review. Int. J. Pharmacognosy Pharm. Sci. 2019;1(1):42-49. DOI: 10.33545/27067009.2019.v1.i1a.82
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